Biomedical Technician - Process Development

Cedars-Sinai Biomanufacturing Center (CBC) is a new 22,000 square feet, state-of-the-art biomanufacturing facility located in West Hollywood, California. The CBC comprises a cGMP cell manufacturing facility housing multiple cleanroom cell production suites and process development rooms for producing the next generation of cell and gene therapies. These new therapies will be used for human IND-enabling clinical trials. With combined expertise in a cGMP-compliant approach to manufacture cells at scale, the CBC will overcome many challenges by building innovative technologies, connecting protocols, up-scaling of processes and achieving Food and Drug Administration standards for all steps involved to bring innovative cell therapy solutions to researchers and translation scientists. With our world-class expertise in stem cell (iPSC) biology, bioprocessing, translational medicine and manufacturing, the CBC is providing a much-needed biomanufacturing center in Southern California! To learn more, please visit: Biomanufacturing Center | Cedars-Sinai (cedars-sinai.edu)

The Biomedical Technician participates on projects to develop and achieve goals related to various projects. Performs tasks associated with the project in accordance to established standard operating procedures (SOP). Responsible for maintaining lab equipment and performing lab maintenance duties including cleaning, sterilization and keep maintenance records. Performs activities strictly according to SOPs, with accurate documentation, and assists cross functional teams with required testing activates as needed. Contributes to the success of projects by keeping accurate and detailed records of experiments and results and will be expected to help supervisor generate reports.

• Performs a variety of cGMP manufacturing production and process development tasks for multiple clients following standard operating procedures for manufacturing processes that will be different for each project based on the types of cells, tissues or organs.
• Performs tissue culture and aseptic techniques for developing and processing clinical grade and research grade cellular products in accordance to established standard operating procedures (SOP).
• Performs cellular, micro- and molecular biology procedures including, but not limited to Western blot, Northern blot, DNA/RNA, Polymerase chain reaction (PCR), protein extraction, cell culture, immunohistochemistry, and staining.
• Assists with process development, validation, and qualification for cellular production for multiple cell lines in GMP/good laboratory practice (GLP) environment.
• Prepares cell culture rooms and research space, including cGMP production rooms, maintains material inventories, and places orders for equipment and supplies.
• Writes and maintains good documentation in laboratory notebooks, data record/transfer, SOPs, and batch records.
• Drafts standard operating procedures and maintains computer database.
• Verifies samples received, logs samples into systems, and transports to appropriate environment within the facility for storage following SOPs.
• Performs lab maintenance duties, including glassware cleaning and sterilization.
• Maintains lab equipment and related records.
• Prepares cGMP production room, maintains material inventories, and places orders for equipment and supplies
• Assists in the operation of specialized equipment and machinery.
• Ensures all activities comply with regulatory guidelines and safety standards.
• Assists with tasks as needed.

• Working Title: Biomedical Technician - Process Development
• Department: CS Biomanufacturing Facility
• Business Entity: Academic / Research
• City: Los Angeles
• Job Category: Biomanufacturing
• Job Specialty: Biomanufacturing
• Position Type: Full-time
• Shift Length: 8 hour shift
• Shift Type: Day